Pick Up Girls

Pick Up Girls

If you want to know how to pick up girls you need to focus on two things. One is knowledge. The other is experience. In general, the more you try to pick up girls the more successful you will be. This is because you’ll gain confidence and insight as you practice. But if you don’t have the knowledge of how to pick up girls, you’ll waste a lot of time and keep striking out. So to score the most dates, start by learning how to pick up girls and then go out and apply your knowledge. The first thing you need to realize is that girls aren’t doing you a favor by talking to you. The majority of them are just as eager to meet a guy as you are to meet them. So have confidence when you approach women. When you talk to a girl you don’t want to ask her permission to talk to her. Consider it a chance for both of you to evaluate the other person. This doesn’t guarantee you success, but it will lessen rejections because the woman will see you as equal instead of her inferior. Before you approach a woman, think about your pickup line. The last thing you want to do is get tongue tied or stumble over your words. So come up with a few pickup lines that won’t come across as desperate or pervy. While it’s good to be prepared, always be flexible. Notice things about the woman you’re approaching and be ready to respond to what she says. Don’t come across as just reading a script. Approach and talk to her The only way to pick up girls is to actually approach and interact with them. Without the willingness to take action in the real world, you can read all the articles in the world and still nothing will change for you. All the clever theories, “pick up lines”, tips and tricks go out the window when you actually take that action step of approaching an attractive girl that you don’t know, starting a conversation with her, and dealing with whatever happens. One good thing about walking over and actually approaching a woman is that you’re automatically demonstrating a certain amount of confidence by actually doing this. This is true in bars and nightclubs, even though girls expect to be approached in these settings, but it’s especially true during the day. Have you ever spotted a woman in a club and went up to buy her a drink? Of course you have, we all have. Did you get her number? Well probably well over half the time she engaged in a little bit of conversation, and left you high and dry. How can you change those odds so that most of the time you are walking away with her number, or even walking away with her on your arm? Here are some basics, and I mean real basics to meeting women that will totally change your game and the results you have been getting for the better. So listen up, cause here we go. If you want to get her number then the best thing you can do is pay her no attention. That is right! Walk up to her group and talk to her friends. Make them laugh, show them some magic, tell a great story. Whatever you do though don’t pay her any attention. Gorgeous women are used to being the center of attention all the time. If you ignore her she will start trying to interject herself into the conversation. When she tries to get into the conversation start off with politely ignoring her, this will drive her crazy and make her try harder. When she tries harder you can joke “Wow she is pushy huh?” to her friends. They will all laugh and this chick will make it her mission to get your attention. Now about ten minutes into this intrigue you tell her friends you need to talk to her. The ways in which a man can gain approval is first and foremost through initial contact of displaying strong and confident body language. The second you come in, nervous, fidgety and talking with a soft and shaky voice, you can pretty much guarantee on being eaten alive. However if you are able to speak confidently, use the right material and convey the right body language then there is no reason as to why you shouldn’t successfully break that bitch barrier, and claim the woman of your choice.

I am danielgabriele read mathematics at Stanford and remained there for his MS. From 1998-1999 on researched in Evolution and in Animal Behavior in Camrbidge, UK. I was was then a professor in the departments of Anthropology and Biology, New Jersy College, USA. Now teaches at the department of Zoology. Carried out research in several areas of evolutionary biology, particularly in sexual selection and the comparative method.

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For every glass of milk, the adjusted hazard ratio of all cause mortality was 1.15 (1.13 to 1.17) in women and 1.03 (1.01 to 1.04) in men. For every glass of milk in women no reduction was observed in fracture risk with higher milk consumption for any fracture (1.02, 1.00 to 1.04) or for hip fracture (1.09, 1.05 to 1.13). The corresponding adjusted hazard ratios in men were 1.01 (0.99 to 1.03) and 1.03 (0.99 to 1.07). In subsamples of two additional cohorts, one in males and one in females, a positive association was seen between milk intake and both urine 8 iso PGF2 (a biomarker of oxidative stress) and serum interleukin 6 (a main inflammatory biomarker).Conclusions High milk intake was associated with higher mortality in one cohort of women and in another cohort of men, and with higher fracture incidence in women. Given the observational study designs with the inherent possibility of residual confounding and reverse causation phenomena, a cautious interpretation of the results is recommended.IntroductionA diet rich in milk products is promoted to reduce the likelihood of osteoporotic fractures. Milk contains 18 of 22 essential nutrients, including calcium, phosphorus, and vitamin D of especial importance for the skeleton. Intestinal uptake of these nutrients is enhanced by the enzymatic capacity to digest lactose into D glucose and D galactose by mutation in the lactase gene, a variant common in those with northern European ancestry.1 2 An intake of dairy foods corresponding to three or four glasses of milk a day has been suggested to save at least 20% of healthcare costs related to osteoporosis.3A high intake of milk might, however, have undesirable effects, because milk is the main dietary source of D galactose. Experimental evidence in several animal species indicates that chronic exposure to D galactose is deleterious to health and the addition of D galactose by injections or in the diet is an established animal model of aging.4 5 6 7 Even a low dose of D galactose induces changes that resemble natural aging in animals, including shortened life span caused by oxidative stress damage, chronic inflammation, neurodegeneration, decreased immune response, and gene transcriptional changes.5 7 A subcutaneous dose of 100 mg/kg D galactose accelerates senescence in mice.5 This is equivalent to 6 10 g in humans, corresponding to 1 2 glasses of milk. Based on a concentration of lactose in cow’s milk of approximately 5%, one glass of milk comprises about 5 g of D galactose. The increase of oxidative stress with aging and chronic low grade inflammation is not only a pathogenetic mechanism of cardiovascular disease and cancer in humans8 9 but also a mechanism of age related bone loss and sarcopenia.9 10 The high amount of lactose and therefore D galactose in milk with theoretical influences on processes such as oxidative stress and inflammation makes the recommendations to increase milk intake for prevention of fractures a conceivable contradiction.Because of the high content of lactose in milk, we hypothesised that high consumption of milk may increase oxidative stress, which in turn affects the risk of mortality and fracture. Meta analyses of cohort studies for the association between dairy and milk intake in relation to mortality11 and fractures12 13 have displayed no clear pattern of risk, and evidence from randomised trials are lacking. Separating milk intake from the consumption of other dairy products may be of importance since a less pronounced induction of oxidative stress and inflammation in humans is expected with cheese and fermented dairy products (for example, soured milk and yogurt) because of their lower or non existent lactose and galactose content,14 15 possible probiotic antioxidant and anti inflammatory effects,16 17 18 and effects on gut microbiota.19 20 21 Indeed, a high intake of fermented milk products has been associated with a decreased risk of cardiovascular diseases,18 22 23 24 whereas a high milk intake is related to a tendency of an unfavourable risk profile for the development of diabetes and cardiovascular disease.18 23 24 We therefore assessed the relation between high milk intake with risk of death and fractures in women and men. We also studied biological markers of oxidative stress and inflammation in relation to milk intake in humans.MethodsWe used two community based cohorts, the Swedish Mammography Cohort25 26 and the Cohort of Swedish Men,27 to analyse the association of milk consumption and mortality and fracture rates. Figure 1 shows the study sample. In 1987 90, all 90303 women aged 39 74 years residing in two Swedish counties (Uppsala and Västmanland, both in central Sweden) received a postal invitation to a routine mammography screening. Enclosed with this invitation was a questionnaire covering both diet (food frequency questionnaire) and lifestyle, which was completed by 74% of the women. In 1997, a subsequent, expanded questionnaire was sent to those who were still living in the study area (response rate 70%). In the present study 61433 women in the Swedish Mammography Cohort with baseline data from 1987 90 and 38984 with updated information from 1997 were available for analysis.The Cohort of Swedish Men was created in the autumn of 1997. All men, aged 45 79 years, residing in Örebro and Västmanland counties in central Sweden were invited to participate in the study (n=100303). Enclosed with this invitation was a questionnaire covering both diet (food frequency questionnaire) and lifestyle, which was completed by 48850 men. Despite the response rate of 49%, the Cohort of Swedish Men is considered representative of Swedish men in this age range in terms of age distribution, educational level, and prevalence of being overweight.27 After exclusions, the final sample included 45339 men (fig 1).Flow chart of study samplesFig 1 Flow chart of study samplesOpen in new tabFood frequency questionnairesThe participants reported their average frequency of consumption of up to 96 foods and beverages during the past year,25 27 28 that is, how many servings, a day or a week, they consumed of common foods, including milk, fermented milk, yogurt, and cheese. Instructions were given that one serving of milk corresponded to one glass of 200 mL. In the first questionnaire in the Swedish Mammography Cohort the categories were prespecified, but in the second questionnaire and the one used in the Cohort of Swedish Men, participants could fill in the exact number of servings of the dairy products (milk, fermented milk, yogurt, and cheese) they consumed a day or a week. Milk intake was specified according to fat content, and we summed intake into a single measure representing total milk intake on a continuous scale. We estimated nutrient intakes by multiplying the consumption frequency of each food item by the nutrient content of age specific portion sizes and reference data obtained from the Swedish National Food Agency database.29 The residual method was used to adjust all nutrient intakes for total energy intake.30 According to validation studies of milk intake, the correlation between the food frequency questionnaire and four, seven day food records every third month, a gold standard reference, has been approximately 0.7.31 Furthermore, in both sexes we have found a positive association between reported intake of milk and the fat tissue content of pentadecanoic acid, a biological marker reflecting average long term intake of milk fat that is, present in both milk and fermented milk products.32 33OutcomesWe considered outcomes registered between study entry (date of mammography screening in 1987 90 for the Swedish Mammography Cohort and 1 January 1998 for the Cohort of Swedish Men) and 31 December 2010. Follow up until death was through the Swedish cause of death registry. Complete linkage with the register is possible by the personal identity number provided to all Swedish residents. We used the underlying cause of death from the Swedish cause of death registry to define mortality from all causes, cardiovascular diseases (international classification of diseases, 10th revision; ICD 10 codes I00 I99), and cancer (ICD 10 C codes). For 1987 to 1996, we used corresponding ICD 9 codes. Accuracy of classification of causes of death in the Swedish registry is high.34We collated fracture events through linkage with the Swedish national patient registry. We defined any fracture event as a hospital admission or an outpatient visit with ICD 10 codes S12 S92. Hip fracture cases were defined by the codes S720 S722. Using a previously validated and accurate method, we separated admissions for incident fracture from readmissions for a previous fracture event.25 35 In analyses we used only the first fracture event. We retained cases of fractures due to suspected high impact trauma in the analysis since there are indications of comparable increases in the risks of low impact and high impact trauma fractures in association with decreasing bone density in elderly people (60 years).36 37 Pathologic fractures as a consequence of a tumour were not included as an outcome.Comorbidity and other additional informationFrom the questionnaires we obtained information on lifestyle, weight, and height. For the Swedish Mammography Cohort the questionnaires also covered information on use of postmenopausal oestrogen therapy, menopausal status, and parity. In the 1997 questionnaires for both cohorts, information was collected on smoking status, ever use of cortisone, and leisure time physical activity during the past year, with five predefined categories ranging from one hour a week to more than five hours a week. This physical activity assessment is valid compared with activity records and accelerometer data.38 We divided educational level into four categories: 12 years, and other (such as vocational). Living alone was categorised based on marital status (yes: unmarried, divorced, widow/widower; no: married, cohabiting). To calculate Charlson’s comorbidity index we collated diagnosis codes from the national patient registry.39 40BiomarkersD galactose supplementation in animals has been shown to increase oxidative stress and inflammation.4 5 6 7 To assess the association between milk intake and biological markers of oxidative stress and inflammation (fig 1), we additionally analysed a clinical subcohort of the Swedish Mammography Cohort25 and the previously described Uppsala Longitudinal Study of Adult Men cohort.41 We assessed food intake by a third food frequency questionnaire in the Swedish Mammography Cohort Clinical (n=5022; mean age 70 years) and by recording diet for one week at age 71 years in the Uppsala Longitudinal Study of Adult Men (n=1138). In 892 women (mean age 70 years) and 633 men (urine collected at age 77) we analysed the urine oxidative stress marker 8 iso PGF2, a dominant F2 isoprostane and an ideal standard biomarker of oxidative stress in vivo.42 We used serum from the same age group in the Uppsala Longitudinal Study of Adult Men to analyse interleukin 6 (a main inflammatory biomarker, n=700).Statistical analysisFor each participant we calculated time at risk until date of each outcome, date of emigration, or the end of the study period (31 December 2010), whichever occurred first. We used Cox proportional hazards regression for estimation of age adjusted and multivariable adjusted hazard ratios and their 95% confidence intervals for prespecified categories of milk intake (18 23 we additionally studied intake of fermented milk and cheese as exposures. The proportional hazard assumptions were confirmed graphically by log log plots. We assessed non linear trends of risk using restricted cubic spline Cox regression with three knots placed at centiles 10, 50, and 90 of the milk product intake.43We used the directed acyclic graph approach44 to select suitable covariates for the multivariable model (see supplementary appendix figure A). The model included age, total energy intake, body mass index, height (all continuous), educational level (9, 10 12, >12 years, other), living alone (yes/no), calcium supplementation (yes/no), vitamin D supplementation (yes/no), ever use of cortisone (yes/no), a healthy dietary pattern, as previously described45 (continuous), physical activity (five categories), smoking status (never, former, current), and the Charlson comorbidity index (continuous, 1 16). We included other potential covariates such as menopausal status; hormone replacement therapy; intakes of calcium, vitamin D, total fat, saturated fat, retinol, alcohol, potassium, phosphorus, and protein; parity; and previous fracture of any type (the last when analysing hip fracture as an outcome, in a second multivariable model to assess whether these covariates confounded or mediated potential associations). In the Swedish Mammography Cohort, of which we had access to information from repeat questionnaires, we time updated exposures and covariates, theoretically yielding stronger outcome associations.46 The analysis in the Cohort of Swedish Men was based on a single exposure assessment. Using the Markov chain Monte Carlo multiple imputation methods, we imputed covariates not assessed in the baseline questionnaire of the Swedish Mammography Cohort in 1987 90 but assessed in the second questionnaire in 1997 (for example, smoking status and physical activity). We performed sensitivity analysis limiting the analysis to baseline data at 1987 90 and 1997 using ordinary Cox’s regression without time updated information. In an additional sensitivity analysis, we adjusted our estimates for milk intake by fermented milk and cheese intakes, and vice versa. We also adjusted our second multivariable model for additional nutrients (except lactose) known to be constituents of milk. Accordingly, we therefore evaluated the change of our hazard ratios after adjustment for intakes of riboflavin, thiamine, niacin, vitamin B6, vitamin B12, folate, carotene, iron, magnesium, sodium, selenium, and zinc.To assess the influence of competing events, we compared cumulative incidence curves for hip fracture, treating death from all causes as competing event, with the Kaplan Meier curves for hip fracture by categories of milk intake.47 Even though competing risk analysis is not considered appropriate for causal analysis, which was the purpose of our study, it can provide additional valuable information for risk prediction.48 We undertook a further sensitivity analysis with any type of vehicle related non fracture incident as an outcome (identified by ICD 10 codes V01 99 excluding simultaneous fracture), which should theoretically be unrelated to consumption of milk. We evaluated whether a history of fracture was associated with milk consumption in the Uppsala Longitudinal Study of Adult Men cohort and whether experiencing a fracture or comorbidity between the first and second food frequency questionnaires was associated with changed milk consumption in the Swedish Mammography Cohort.Finally, we used cubic spline regression analysis to assess the relation between intake of milk, fermented milk, or yogurt, cheese, the urine oxidative stress marker 8 iso PGF2, and serum interleukin 6. Before analysis we log transformed both biomarkers because of their skewed distributions. We adjusted the estimates for age, body mass index, energy intake, education (four categories), smoking status (never, former, current), and physical activity (four categories). The statistical analyses were performed with STATA 11.2 (StataCorp, College Station, TX) and SAS, version 9.3 (SAS Institute, Cary, NC).ResultsTable 1 lists the characteristics of the study participants by categories of milk intake. Mean intake of milk at baseline in the Swedish Mammography Cohort was 240 g a day and in the Cohort of Swedish Men was 290 g a day. With increasing categories of milk intake the reported intake for most other nutrients, including energy intake, also increased, although alcohol intake tended to decrease. There were generally small differences between categories of milk intake in body stature, nutritional supplement use, marital status, comorbidity, educational level, smoking status, and physical activity level.Table 1 Baseline characteristics of women in Swedish Mammography Cohort (1987 90) and men in Cohort of Swedish Men (1997) by categories of milk intake. Values are numbers (percentages) unless stated otherwisemillion heist at Bellagio casino

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